Macias NMR
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Description: Web Page of the NMR Group of Dr. Maria J. Macias.
Structural characterization of macromolecular assemblies We study how Smad proteins and bound cofactors assemble and read DNA, to correlate cell signaling with gene expression. Cell fate is controlled by a multitude of signals and loss of this control has devastating consequences for living organisms. One of the key players in this network of signals is the TGF-beta family of cytokines. These hormones trigger an immense amount of responses by sending activated Smad transcription factors (Sma and Mad related proteins) to the nucleus where participate in many processes including the control of stem cell pluripotency and differentiation. At a molecular level, the basis for the transmission of information is the organization of complex networks orchestrated by Smads; many of which involve protein-protein and protein-DNA interactions.
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WEBSITE Info
| Page title: | About us | Macias Group |
| Keywords: | |
| Description: | |
| IP-address: | 161.116.107.57 |
WHOIS Info
| NS | Name Server: DNS5.SERVIDORESDNS.NET Name Server: DNS6.SERVIDORESDNS.NET |
| WHOIS | Status: ok |
| Date | Creation Date: 31-jan-2005 Expiration Date: 31-jan-2015 |