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Currarino Syndrome

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Scan day: 13 February 2014 UTC
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Description: Paper by Sally Ann Lynch.
Atlas of Genetics and Cytogenetics in Oncology and Haematology Anal atresia, sacral anomalies, presacral mass (ASP) Sacral defect with anterior meningocoele Currarino syndrome is a multiple congenital anomalies syndrome characterized by partial agenesis of the sacrum in association with pelvic malformation. Anal atresia and the presence of a pre-sacral mass (teratoma and/or anterior meningocoele) make up the so called Currarino triad. Other malformations, such as renal (35%) and gynaecological (19%) are common. Hirschsprungs diseasehas also been recorded. Other rarer complications include pelvic abcess, malignant degeneration of a pre-sacral teratoma, E Coli ascending meningitis and spinal cord tethering. Recurrence of a benign teratoma has been recorded. Urinary incontinence, dysmenorrhoea, dyspareunia, poor sphincter control, sacral anaesthesia and headaches precipitated by coughing or straining have been reported.
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Page title:Currarino syndrome
Keywords:Currarino syndrome, Currarino triad, Anal atresia, sacral anomalies, presacral mass (ASP), Sacral defect with anterior meningocoele, Cancer-Prone Diseases, Inherited cancer. HLXB9,
Description:Currarino syndrome, Authors: Sally Ann Lynch. Published in: Atlas Genet Cytogenet Oncol Haematol.
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