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Canine Von Willebrand's Disease

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Description: Information on this disease from the Jack Russell Terrier Club of America.
Jack Russell Terrier JRTCA : Medical - Canine Von Willebrand's Disease Preserve, Protect and Work the Jack Russell Terrier Canine Von Willebrand's Disease in Jack Russell Terriers Von Willebrand's disease (VvWD) is an inherited bleeding disorder. It is a complex and difficult disorder to deal with, because genetics, diagnostic abnormalities, pathogenic mechanisms, and sometimes conflicting clinical signs are all involved. The commonality between all vWD is a reduction in the amount or function of von Willebrand factor (vWF), which is manifested through abnormal platelet function and prolonged bleeding time. The vWF factor is a blood protein which binds platelets to blood vessels when they are injured. Absence or deficiency of the factor can, therefore, lead to uncontrolled bleeding episodes. In dogs, the most common clinical signs are spontaneous bleeding from the gums or nose, blood in the urine or gastrointestinal tract, or excessive bleeding at the time of surgery. Clinical signs also include epistaxis, prolonged estrus or postpartum bleeding, hematuria, melena, excessive bleeding after toe-nail cutting and sometimes hemorrhaging into body cavities and organs.
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Page title:Jack Russell Terrier JRTCA : Medical - Canine Von Willebrand's Disease
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Description:Von Willebrand's disease (VvWD) is an inherited bleeding disorder in Jack Russell Terriers.
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