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VIN: Polyuria, Polydipsia and Diabetes Insipidus

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Description: Conference presentation by Richard W. Nelson, DVM, on distinguishing Diabetes insipidus from other conditions that cause excessive thirst and urination.
PUPD and Diabetes Insipidus - WSAVA 2002 Polyuria, Polydipsia and Diabetes Insipidus Richard W. Nelson, DVM, Diplomate ACVIM School of Veterinary Medicine, University of California Water consumption and urine production are controlled by complex interactions among plasma osmolality and volume, the thirst center, the kidney, the pituitary gland, and the hypothalamus. Dysfunction in any of these areas results in the clinical signs of polyuria (PU) and polydipsia (PD). A variety of metabolic disturbances can cause PU/PD (Table 1). Perhaps the least common but most interesting is diabetes insipidus (DI).
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